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Antigen Presentation and T-Cell Activation Are Critical for RBP4-Induced Insulin Resistance
Adipose tissue (AT) inflammation contributes to impaired insulin action, which is a major cause of type 2 diabetes. RBP4 is an adipocyte- and liver-derived protein with an important role in insulin resistance, metabolic syndrome, and AT inflammation. RBP4 elevation causes AT inflammation by activati...
Autores principales: | Moraes-Vieira, Pedro M., Castoldi, Angela, Aryal, Pratik, Wellenstein, Kerry, Peroni, Odile D., Kahn, Barbara B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839203/ https://www.ncbi.nlm.nih.gov/pubmed/26936962 http://dx.doi.org/10.2337/db15-1696 |
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