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Environmental Correlation Analysis for Genes Associated with Protection against Malaria
Genome-wide searches for loci involved in human resistance to malaria are currently being conducted on a large scale in Africa using case-control studies. Here, we explore the utility of an alternative approach—“environmental correlation analysis, ECA,” which tests for clines in allele frequencies a...
Autores principales: | Mackinnon, Margaret J., Ndila, Carolyne, Uyoga, Sophie, Macharia, Alex, Snow, Robert W., Band, Gavin, Rautanen, Anna, Rockett, Kirk A., Kwiatkowski, Dominic P., Williams, Thomas N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839215/ https://www.ncbi.nlm.nih.gov/pubmed/26744416 http://dx.doi.org/10.1093/molbev/msw004 |
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