Cell-penetrating peptides—the Swiss Army knife of cancer vaccines

Therapeutic cancer vaccination is an attractive treatment modality for cancer, but with limitations using existing whole-cell, peptide, or protein vaccines. We propose that a cell-penetrating peptide (CPP)-based vaccine delivering multi-epitopic antigens into antigen-presenting cells (APCs) offers g...

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Detalles Bibliográficos
Autores principales: Walker, Paul R., Belnoue, Elodie, Dietrich, Pierre-Yves, Derouazi, Madiha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839312/
https://www.ncbi.nlm.nih.gov/pubmed/27141358
http://dx.doi.org/10.1080/2162402X.2015.1095435
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author Walker, Paul R.
Belnoue, Elodie
Dietrich, Pierre-Yves
Derouazi, Madiha
author_facet Walker, Paul R.
Belnoue, Elodie
Dietrich, Pierre-Yves
Derouazi, Madiha
author_sort Walker, Paul R.
collection PubMed
description Therapeutic cancer vaccination is an attractive treatment modality for cancer, but with limitations using existing whole-cell, peptide, or protein vaccines. We propose that a cell-penetrating peptide (CPP)-based vaccine delivering multi-epitopic antigens into antigen-presenting cells (APCs) offers great potential to induce an integrated antitumor immune response and robust, sustained therapeutic effect.
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spelling pubmed-48393122016-05-02 Cell-penetrating peptides—the Swiss Army knife of cancer vaccines Walker, Paul R. Belnoue, Elodie Dietrich, Pierre-Yves Derouazi, Madiha Oncoimmunology Author's View Therapeutic cancer vaccination is an attractive treatment modality for cancer, but with limitations using existing whole-cell, peptide, or protein vaccines. We propose that a cell-penetrating peptide (CPP)-based vaccine delivering multi-epitopic antigens into antigen-presenting cells (APCs) offers great potential to induce an integrated antitumor immune response and robust, sustained therapeutic effect. Taylor & Francis 2015-12-10 /pmc/articles/PMC4839312/ /pubmed/27141358 http://dx.doi.org/10.1080/2162402X.2015.1095435 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Walker, Paul R.
Belnoue, Elodie
Dietrich, Pierre-Yves
Derouazi, Madiha
Cell-penetrating peptides—the Swiss Army knife of cancer vaccines
title Cell-penetrating peptides—the Swiss Army knife of cancer vaccines
title_full Cell-penetrating peptides—the Swiss Army knife of cancer vaccines
title_fullStr Cell-penetrating peptides—the Swiss Army knife of cancer vaccines
title_full_unstemmed Cell-penetrating peptides—the Swiss Army knife of cancer vaccines
title_short Cell-penetrating peptides—the Swiss Army knife of cancer vaccines
title_sort cell-penetrating peptides—the swiss army knife of cancer vaccines
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839312/
https://www.ncbi.nlm.nih.gov/pubmed/27141358
http://dx.doi.org/10.1080/2162402X.2015.1095435
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