POLE proofreading mutation, immune response and prognosis in endometrial cancer

Endometrial cancers (ECs) with POLE proofreading mutations are typified by ultramutation and excellent prognosis. We investigated whether these were related, and found that POLE-mutant ECs display a robust T cell response that corresponds to an enrichment of antigenic tumor neopeptides. Enhanced imm...

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Bibliographic Details
Main Authors: van Gool, Inge C., Bosse, Tjalling, Church, David N.
Format: Online Article Text
Language:English
Published: Taylor & Francis 2015
Subjects:
Author's View
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839358/
https://www.ncbi.nlm.nih.gov/pubmed/27141333
http://dx.doi.org/10.1080/2162402X.2015.1072675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839358/
https://www.ncbi.nlm.nih.gov/pubmed/27141333
http://dx.doi.org/10.1080/2162402X.2015.1072675

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