Učitavanje…

POLE proofreading mutation, immune response and prognosis in endometrial cancer

Endometrial cancers (ECs) with POLE proofreading mutations are typified by ultramutation and excellent prognosis. We investigated whether these were related, and found that POLE-mutant ECs display a robust T cell response that corresponds to an enrichment of antigenic tumor neopeptides. Enhanced imm...

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Bibliografski detalji
Glavni autori: van Gool, Inge C., Bosse, Tjalling, Church, David N.
Format: Online Članak Tekst
Jezik:English
Izdano: Taylor & Francis 2015
Teme:
Online pristup:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839358/
https://www.ncbi.nlm.nih.gov/pubmed/27141333
http://dx.doi.org/10.1080/2162402X.2015.1072675