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POLE proofreading mutation, immune response and prognosis in endometrial cancer
Endometrial cancers (ECs) with POLE proofreading mutations are typified by ultramutation and excellent prognosis. We investigated whether these were related, and found that POLE-mutant ECs display a robust T cell response that corresponds to an enrichment of antigenic tumor neopeptides. Enhanced imm...
| Հիմնական հեղինակներ: | , , |
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| Ձևաչափ: | Online Հոդված Տեքստ |
| Լեզու: | English |
| Հրապարակվել է: |
Taylor & Francis
2015
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| Խորագրեր: | |
| Առցանց հասանելիություն: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839358/ https://www.ncbi.nlm.nih.gov/pubmed/27141333 http://dx.doi.org/10.1080/2162402X.2015.1072675 |