POLE proofreading mutation, immune response and prognosis in endometrial cancer

Endometrial cancers (ECs) with POLE proofreading mutations are typified by ultramutation and excellent prognosis. We investigated whether these were related, and found that POLE-mutant ECs display a robust T cell response that corresponds to an enrichment of antigenic tumor neopeptides. Enhanced imm...

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Detaylı Bibliyografya
Asıl Yazarlar: van Gool, Inge C., Bosse, Tjalling, Church, David N.
Materyal Türü: Online Makale Metin
Dil:English
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Author's View
Online Erişim:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839358/
https://www.ncbi.nlm.nih.gov/pubmed/27141333
http://dx.doi.org/10.1080/2162402X.2015.1072675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839358/
https://www.ncbi.nlm.nih.gov/pubmed/27141333
http://dx.doi.org/10.1080/2162402X.2015.1072675

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