Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

Tumor-derived microvesicles (TD-MVs) are key mediators which are shed by cancer cells and can sensitize neighboring cells in the tumor microenvironment. TD-MVs are extracellular vesicles composed of exosomes and MVs and promote cancer invasion and metastasis. Intratumoral hypoxia is an integral comp...

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Detalles Bibliográficos
Autores principales: Berchem, Guy, Noman, Muhammad Zaeem, Bosseler, Manon, Paggetti, Jerome, Baconnais, Sonia, Le cam, Eric, Nanbakhsh, Arash, Moussay, Etienne, Mami-Chouaib, Fathia, Janji, Bassam, Chouaib, Salem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839360/
https://www.ncbi.nlm.nih.gov/pubmed/27141372
http://dx.doi.org/10.1080/2162402X.2015.1062968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839360/
https://www.ncbi.nlm.nih.gov/pubmed/27141372
http://dx.doi.org/10.1080/2162402X.2015.1062968

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