In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer

Metastatic breast cancer remains an incurable disease. Most patients experience objective treatment responses associated with palliation of symptoms; however, progression inevitably occurs. Thus, there is an urgent need for innovative therapeutic strategies that may halt disease progression. Adoptiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Thakur, Archana, Lum, Lawrence G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839366/
https://www.ncbi.nlm.nih.gov/pubmed/27141330
http://dx.doi.org/10.1080/2162402X.2015.1055061
_version_ 1782428129194672128
author Thakur, Archana
Lum, Lawrence G.
author_facet Thakur, Archana
Lum, Lawrence G.
author_sort Thakur, Archana
collection PubMed
description Metastatic breast cancer remains an incurable disease. Most patients experience objective treatment responses associated with palliation of symptoms; however, progression inevitably occurs. Thus, there is an urgent need for innovative therapeutic strategies that may halt disease progression. Adoptive T-cell therapy is a potent and promising treatment option with the potential to harness the intrinsic antitumor power of the immune system and provide long-term immunity against cancer.
format Online
Article
Text
id pubmed-4839366
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-48393662016-05-02 In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer Thakur, Archana Lum, Lawrence G. Oncoimmunology Author's View Metastatic breast cancer remains an incurable disease. Most patients experience objective treatment responses associated with palliation of symptoms; however, progression inevitably occurs. Thus, there is an urgent need for innovative therapeutic strategies that may halt disease progression. Adoptive T-cell therapy is a potent and promising treatment option with the potential to harness the intrinsic antitumor power of the immune system and provide long-term immunity against cancer. Taylor & Francis 2015-07-15 /pmc/articles/PMC4839366/ /pubmed/27141330 http://dx.doi.org/10.1080/2162402X.2015.1055061 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Thakur, Archana
Lum, Lawrence G.
In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer
title In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer
title_full In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer
title_fullStr In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer
title_full_unstemmed In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer
title_short In Situ immunization by bispecific antibody targeted T cell therapy in breast cancer
title_sort in situ immunization by bispecific antibody targeted t cell therapy in breast cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839366/
https://www.ncbi.nlm.nih.gov/pubmed/27141330
http://dx.doi.org/10.1080/2162402X.2015.1055061
work_keys_str_mv AT thakurarchana insituimmunizationbybispecificantibodytargetedtcelltherapyinbreastcancer
AT lumlawrenceg insituimmunizationbybispecificantibodytargetedtcelltherapyinbreastcancer

Ejemplares similares