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Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the antitumor immunity and efficacy against melanoma

The stimulation of the immune system using oncolytic adenoviruses (OAds) has attracted significant interest and several studies suggested that OAds immunogenicity might be important for their efficacy. Therefore, we developed a versatile and rapid system to adsorb tumor-specific major histocompatibi...

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Detalles Bibliográficos
Autores principales: Capasso, Cristian, Hirvinen, Mari, Garofalo, Mariangela, Romaniuk, Dmitrii, Kuryk, Lukasz, Sarvela, Teea, Vitale, Andrea, Antopolsky, Maxim, Magarkar, Aniket, Viitala, Tapani, Suutari, Teemu, Bunker, Alex, Yliperttula, Marjo, Urtti, Arto, Cerullo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839367/
https://www.ncbi.nlm.nih.gov/pubmed/27141389
http://dx.doi.org/10.1080/2162402X.2015.1105429