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Pharmacological DNA demethylation: Implications for cancer immunotherapy

Recent studies have demonstrated that DNA demethylation agents can mimic a viral infection by induction of dsRNAs. This viral mimicry leads to an antiviral response mediated by the cytosolic pattern recognition receptor MDA5, followed by MAVS (IPS1) activation, IRF7 nuclear translocation and upregul...

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Detalles Bibliográficos
Autores principales:	Roulois, David, Yau, Helen Loo, De Carvalho, Daniel D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839380/ https://www.ncbi.nlm.nih.gov/pubmed/27141349 http://dx.doi.org/10.1080/2162402X.2015.1090077

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