Bovine herpesvirus 4-based vector delivering a hybrid rat/human HER-2 oncoantigen efficiently protects mice from autochthonous Her-2(+) mammary cancer

The epidermal growth factor receptor 2 (HER-2) oncogene is a major target for the immunotherapy of breast cancer. Following up to the therapeutic success achieved with Her-2-targeting monoclonal antibodies, immune-prophylactic approaches directed against Her-2 have also been investigated taking into...

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Detalles Bibliográficos
Autores principales: Jacca, Sarah, Rolih, Valeria, Quaglino, Elena, Franceschi, Valentina, Tebaldi, Giulia, Bolli, Elisabetta, Rosamilia, Alfonso, Ottonello, Simone, Cavallo, Federica, Donofrio, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839386/
https://www.ncbi.nlm.nih.gov/pubmed/27141335
http://dx.doi.org/10.1080/2162402X.2015.1082705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839386/
https://www.ncbi.nlm.nih.gov/pubmed/27141335
http://dx.doi.org/10.1080/2162402X.2015.1082705

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