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Bovine herpesvirus 4-based vector delivering a hybrid rat/human HER-2 oncoantigen efficiently protects mice from autochthonous Her-2(+) mammary cancer
The epidermal growth factor receptor 2 (HER-2) oncogene is a major target for the immunotherapy of breast cancer. Following up to the therapeutic success achieved with Her-2-targeting monoclonal antibodies, immune-prophylactic approaches directed against Her-2 have also been investigated taking into...
Autores principales: | Jacca, Sarah, Rolih, Valeria, Quaglino, Elena, Franceschi, Valentina, Tebaldi, Giulia, Bolli, Elisabetta, Rosamilia, Alfonso, Ottonello, Simone, Cavallo, Federica, Donofrio, Gaetano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839386/ https://www.ncbi.nlm.nih.gov/pubmed/27141335 http://dx.doi.org/10.1080/2162402X.2015.1082705 |
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