Cargando…

Genetic Associations With White Matter Hyperintensities Confer Risk of Lacunar Stroke

BACKGROUND AND PURPOSE—: White matter hyperintensities (WMH) are increased in patients with lacunar stroke. Whether this is because of shared pathogenesis remains unknown. Using genetic data, we evaluated whether WMH-associated genetic susceptibility factors confer risk of lacunar stroke, and theref...

Descripción completa

Detalles Bibliográficos
Autores principales:	Traylor, Matthew, Rutten-Jacobs, Loes C.A., Thijs, Vincent, Holliday, Elizabeth G., Levi, Chris, Bevan, Steve, Malik, Rainer, Boncoraglio, Giorgio, Sudlow, Cathie, Rothwell, Peter M., Dichgans, Martin, Markus, Hugh S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2016
Materias:	Original Contributions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839546/ https://www.ncbi.nlm.nih.gov/pubmed/27073246 http://dx.doi.org/10.1161/STROKEAHA.115.011625

Ejemplares similares

Differences in Common Genetic Predisposition to Ischemic Stroke by Age and Sex
por: Traylor, Matthew, et al.
Publicado: (2015)

Common NOTCH3 Variants and Cerebral Small-Vessel Disease
por: Rutten-Jacobs, Loes C.A., et al.
Publicado: (2015)

Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype
por: Rutten-Jacobs, Loes C.A., et al.
Publicado: (2016)

Genetic Architecture of White Matter Hyperintensities Differs in Hypertensive and Nonhypertensive Ischemic Stroke
por: Adib-Samii, Poneh, et al.
Publicado: (2015)

Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)
por: Traylor, Matthew, et al.
Publicado: (2019)

Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia
por: Rutten-Jacobs, Loes C.A., et al.
Publicado: (2018)

Vascular Risk Factor Profiles Differ Between Magnetic Resonance Imaging-Defined Subtypes of Younger-Onset Lacunar Stroke
por: Rutten-Jacobs, Loes C.A., et al.
Publicado: (2017)

Genetic Architecture of Lacunar Stroke
por: Traylor, Matthew, et al.
Publicado: (2015)

Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants
por: Larsson, Susanna C, et al.
Publicado: (2018)

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke
por: Traylor, Matthew, et al.
Publicado: (2016)

Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke
por: Hanscombe, Ken B., et al.
Publicado: (2015)

Progression of White Matter Hyperintensities Contributes to Lacunar Infarction
por: Xu, Xin, et al.
Publicado: (2018)

Causal Impact of Type 2 Diabetes Mellitus on Cerebral Small Vessel Disease: A Mendelian Randomization Analysis
por: Liu, Junfeng, et al.
Publicado: (2018)

Cognitive Impact of Lacunar Infarcts and White Matter Hyperintensity Volume
por: Warren, Matthew W., et al.
Publicado: (2015)

Hemispheric Asymmetry of White Matter Hyperintensity in Association With Lacunar Infarction
por: Ryu, Wi‐Sun, et al.
Publicado: (2018)

Prevalence of CADASIL and Fabry Disease in a Cohort of MRI Defined Younger Onset Lacunar Stroke
por: Kilarski, Laura L., et al.
Publicado: (2015)

Lacunar Stroke Lesion Extent and Location and White Matter Hyperintensities Evolution 1 Year Post-lacunar Stroke
por: Valdés Hernández, Maria del C., et al.
Publicado: (2021)

Oxidative phosphorylation and lacunar stroke: Genome-wide enrichment analysis of common variants
por: Traylor, Matthew, et al.
Publicado: (2016)

Heterogeneity of White Matter Hyperintensity and Cognitive Impairment in Patients with Acute Lacunar Stroke
por: Ye, Mengfan, et al.
Publicado: (2022)

Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients
por: Loos, Caroline M. J., et al.
Publicado: (2015)

Long-term mortality and recurrent vascular events in lacunar versus non-lacunar ischaemic stroke: A cohort study
por: Portegijs, Suzanne, et al.
Publicado: (2021)

Plasma tPA-Activity and Progression of Cerebral White Matter Hyperintensities in Lacunar Stroke Patients
por: van Overbeek, Ellen C., et al.
Publicado: (2016)

Age and recurrent stroke are related to the severity of white matter hyperintensities in lacunar infarction patients with diabetes
por: Yu, Ling, et al.
Publicado: (2018)

White-Matter Hyperintensities and Lacunar Infarcts Are Associated with an Increased Risk of Alzheimer's Disease in the Elderly in China
por: Ye, Shuai, et al.
Publicado: (2019)

Regional white matter hyperintensity volume predicts persistent cognitive impairment in acute lacunar infarct patients
por: Li, Tan, et al.
Publicado: (2023)

Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging
por: Loos, Caroline M.J., et al.
Publicado: (2018)

Post-stroke Cognition at 1 and 3 Years Is Influenced by the Location of White Matter Hyperintensities in Patients With Lacunar Stroke
por: Valdés Hernández, Maria del C., et al.
Publicado: (2021)

Genome‐wide meta‐analysis identifies 3 novel loci associated with stroke
por: Malik, Rainer, et al.
Publicado: (2018)

Lacunar Infarcts, but Not Perivascular Spaces, Are Predictors of Cognitive Decline in Cerebral Small-Vessel Disease
por: Benjamin, Philip, et al.
Publicado: (2018)

Modifiable Lifestyle Factors and Risk of Stroke: A Mendelian Randomization Analysis
por: Harshfield, Eric L., et al.
Publicado: (2021)

Genes From a Translational Analysis Support a Multifactorial Nature of White Matter Hyperintensities
por: Lopez, Lorna M., et al.
Publicado: (2015)

Do Regions of Increased Inflammation Progress to New White Matter Hyperintensities?: A Longitudinal Positron Emission Tomography-Magnetic Resonance Imaging Study
por: Tozer, Daniel J., et al.
Publicado: (2023)

Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?: A Genetic Study
por: Brown, Robin B., et al.
Publicado: (2019)

Different Types of White Matter Hyperintensities in CADASIL
por: Duchesnay, Edouard, et al.
Publicado: (2018)

Improving Clinical Detection of Acute Lacunar Stroke: Analysis From the IST-3
por: Arba, Francesco, et al.
Publicado: (2020)

Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies
por: Traylor, Matthew, et al.
Publicado: (2021)

White Matter Hyperintensity Volume and Poststroke Cognition: An Individual Patient Data Pooled Analysis of 9 Ischemic Stroke Cohort Studies
por: de Kort, Floor A.S., et al.
Publicado: (2023)

Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes: A Mendelian Randomization Study
por: Georgakis, Marios K., et al.
Publicado: (2020)

Spatial Relation Between White Matter Hyperintensities and Incident Lacunes of Presumed Vascular Origin: A 14-Year Follow-Up Study
por: Yi, Fang, et al.
Publicado: (2022)

A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach
por: Traylor, Matthew, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_hkpsn1o7go0o5ru6mdb3e0cte4