Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors

The inevitable switch from standard molecular methods to next-generation sequencing for the molecular profiling of tumors is challenging for most diagnostic laboratories. However, fixed validation criteria for diagnostic accreditation are not in place because of the great variability in methods and...

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Detalles Bibliográficos
Autores principales: Froyen, Guy, Broekmans, An, Hillen, Femke, Pat, Karin, Achten, Ruth, Mebis, Jeroen, Rummens, Jean-Luc, Willemse, Johan, Maes, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839685/
https://www.ncbi.nlm.nih.gov/pubmed/27101000
http://dx.doi.org/10.1371/journal.pone.0154038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839685/
https://www.ncbi.nlm.nih.gov/pubmed/27101000
http://dx.doi.org/10.1371/journal.pone.0154038

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