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Export of Precursor tRNA(Ile) from the Nucleus to the Cytoplasm in Human Cells
In the current concept, tRNA maturation in vertebrate cells, including splicing of introns, trimming of 5’ leader and 3’ trailer, and adding of CCA, is thought to occur exclusively in the nucleus. Here we provide evidence to challenge this concept. Unspliced intron-containing precursor tRNA(Ile) was...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839721/ https://www.ncbi.nlm.nih.gov/pubmed/27101286 http://dx.doi.org/10.1371/journal.pone.0154044 |