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Single-Cell Co-expression Analysis Reveals Distinct Functional Modules, Co-regulation Mechanisms and Clinical Outcomes
Co-expression analysis has been employed to predict gene function, identify functional modules, and determine tumor subtypes. Previous co-expression analysis was mainly conducted at bulk tissue level. It is unclear whether co-expression analysis at the single-cell level will provide novel insights i...
Autores principales: | Wang, Jie, Xia, Shuli, Arand, Brian, Zhu, Heng, Machiraju, Raghu, Huang, Kun, Ji, Hongkai, Qian, Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839722/ https://www.ncbi.nlm.nih.gov/pubmed/27100869 http://dx.doi.org/10.1371/journal.pcbi.1004892 |
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