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Conventional and Regulatory CD4(+) T Cells That Share Identical TCRs Are Derived from Common Clones
Results from studies comparing the diversity and specificity of the TCR repertoires expressed by conventional (Tconv) and regulatory (Treg) CD4(+) T cell have varied depending on the experimental system employed. We developed a new model in which T cells express a single fixed TCRα chain, randomly r...
Autores principales: | Wolf, Kyle J., Emerson, Ryan O., Pingel, Jeanette, Buller, R. Mark, DiPaolo, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839724/ https://www.ncbi.nlm.nih.gov/pubmed/27100298 http://dx.doi.org/10.1371/journal.pone.0153705 |
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