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Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis

Pannexin1 (Panx1) subunits oligomerize to form large-pore channels between the intracellular and extracellular milieu that have been shown to regulate proliferation, differentiation and cell death mechanisms. These key cellular responses are ultimately necessary for normal tissue development and fun...

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Detalles Bibliográficos
Autores principales: Stewart, Michael K. G., Plante, Isabelle, Penuela, Silvia, Laird, Dale W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839729/
https://www.ncbi.nlm.nih.gov/pubmed/27099931
http://dx.doi.org/10.1371/journal.pone.0154162