Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human

Alkylating agents are a key component of cancer chemotherapy. Several cellular mechanisms are known to be important for its survival, particularly DNA repair and xenobiotic detoxification, yet genomic screens indicate that additional cellular components may be involved. Elucidating these components...

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Detalles Bibliográficos
Autores principales: Zanotto-Filho, Alfeu, Dashnamoorthy, Ravi, Loranc, Eva, de Souza, Luis H. T., Moreira, José C. F., Suresh, Uthra, Chen, Yidong, Bishop, Alexander J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839732/
https://www.ncbi.nlm.nih.gov/pubmed/27100653
http://dx.doi.org/10.1371/journal.pone.0153970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839732/
https://www.ncbi.nlm.nih.gov/pubmed/27100653
http://dx.doi.org/10.1371/journal.pone.0153970

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