Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs

Fifteen different ligands, including heparin (Hep), are cleared from lymph and blood by the Hyaluronan (HA) Receptor for Endocytosis (HARE; derived from Stabilin-2 by proteolysis), which contains four endocytic motifs (M1-M4). Endocytosis of HARE•Hep complexes is targeted to coated pits by M1, M2, a...

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Detalles Bibliográficos
Autores principales: Pandey, Madhu S., Miller, Colton M., Harris, Edward N., Weigel, Paul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839745/
https://www.ncbi.nlm.nih.gov/pubmed/27100626
http://dx.doi.org/10.1371/journal.pone.0154124

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