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Variations in the Processing of DNA Double-Strand Breaks Along 60-MeV Therapeutic Proton Beams

PURPOSE: To investigate the variations in induction and repair of DNA damage along the proton path, after a previous report on the increasing biological effectiveness along clinically modulated 60-MeV proton beams. METHODS AND MATERIALS: Human skin fibroblast (AG01522) cells were irradiated along a...

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Detalles Bibliográficos
Autores principales: Chaudhary, Pankaj, Marshall, Thomas I., Currell, Frederick J., Kacperek, Andrzej, Schettino, Giuseppe, Prise, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840231/
https://www.ncbi.nlm.nih.gov/pubmed/26452569
http://dx.doi.org/10.1016/j.ijrobp.2015.07.2279