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Antigen-specific T cells fully conserve antitumour function following cryopreservation

Immunotherapies based on the autologous adoptive transfer of ex vivo-manipulated T cells are rapidly evolving for the treatment of both metastatic and primary malignancies. However, extended ex vivo culturing reduces the functionality of isolated T cells. Cryopreservation of rapidly expanded T cells...

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Detalles Bibliográficos
Autores principales: Galeano Niño, Jorge L, Kwan, Rain YQ, Weninger, Wolfgang, Biro, Maté
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840239/
https://www.ncbi.nlm.nih.gov/pubmed/26754453
http://dx.doi.org/10.1038/icb.2015.105

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