Evolving adaptive immunity

Generation of a diverse repertoire of antigen receptor specificities via DNA recombination underpins adaptive immunity. In this issue of Genes & Development, Carmona and colleagues (pp. 909–917) provide novel insights into the origin and function of recombination-activating gene 1 (RAG1) and RAG...

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Detalles Bibliográficos
Autores principales: Lovely, Geoffrey A., Sen, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Outlook
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840292/
https://www.ncbi.nlm.nih.gov/pubmed/27083993
http://dx.doi.org/10.1101/gad.281014.116
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author Lovely, Geoffrey A.
Sen, Ranjan
author_facet Lovely, Geoffrey A.
Sen, Ranjan
author_sort Lovely, Geoffrey A.
collection PubMed
description Generation of a diverse repertoire of antigen receptor specificities via DNA recombination underpins adaptive immunity. In this issue of Genes & Development, Carmona and colleagues (pp. 909–917) provide novel insights into the origin and function of recombination-activating gene 1 (RAG1) and RAG2, the lymphocyte-specific components of the recombinase involved in the process.
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spelling pubmed-48402922016-10-15 Evolving adaptive immunity Lovely, Geoffrey A. Sen, Ranjan Genes Dev Outlook Generation of a diverse repertoire of antigen receptor specificities via DNA recombination underpins adaptive immunity. In this issue of Genes & Development, Carmona and colleagues (pp. 909–917) provide novel insights into the origin and function of recombination-activating gene 1 (RAG1) and RAG2, the lymphocyte-specific components of the recombinase involved in the process. Cold Spring Harbor Laboratory Press 2016-04-15 /pmc/articles/PMC4840292/ /pubmed/27083993 http://dx.doi.org/10.1101/gad.281014.116 Text en Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Outlook
Lovely, Geoffrey A.
Sen, Ranjan
Evolving adaptive immunity
title Evolving adaptive immunity
title_full Evolving adaptive immunity
title_fullStr Evolving adaptive immunity
title_full_unstemmed Evolving adaptive immunity
title_short Evolving adaptive immunity
title_sort evolving adaptive immunity
topic Outlook
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840292/
https://www.ncbi.nlm.nih.gov/pubmed/27083993
http://dx.doi.org/10.1101/gad.281014.116
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