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Interaction between IGFBP7 and insulin: a theoretical and experimental study

Insulin-like growth factor binding protein 7 (IGFBP7) can bind to insulin with high affinity which inhibits the early steps of insulin action. Lack of recognition mechanism impairs our understanding of insulin regulation before it binds to insulin receptor. Here we combine computational simulations...

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Detalles Bibliográficos
Autores principales:	Ruan, Wenjing, Kang, Zhengzhong, Li, Youzhao, Sun, Tianyang, Wang, Lipei, Liang, Lijun, Lai, Maode, Wu, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840315/ https://www.ncbi.nlm.nih.gov/pubmed/27101796 http://dx.doi.org/10.1038/srep19586

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