Cargando…

Soluble VEGF receptor 1 (sFLT1) induces non-apoptotic death in ovarian and colorectal cancer cells

Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR1/sFLT1) is an angiogenesis inhibitor that competes with angiogenic factors such as VEGF and Placental Growth Factor (PlGF). Imbalances of VEGF and sFLT1 levels can cause pathological conditions such as tumour growth or preeclampsia. We ob...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miyake, Tatsuya, Kumasawa, Keiichi, Sato, Noriko, Takiuchi, Tsuyoshi, Nakamura, Hitomi, Kimura, Tadashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840331/ https://www.ncbi.nlm.nih.gov/pubmed/27103202 http://dx.doi.org/10.1038/srep24853

Ejemplares similares

The Soluble VEGF Receptor sFlt-1 Contributes to Impaired Neovascularization in Aged Mice
por: Zhao, Guangxian, et al.
Publicado: (2017)

The soluble VEGF receptor sFlt-1 contributes to endothelial dysfunction in IgA nephropathy
por: Zhai, Yaling, et al.
Publicado: (2020)

Elevated Soluble VEGF Receptor sFlt-1 Correlates with Endothelial Injury in IgA Nephropathy
por: Zhai, Ya-Ling, et al.
Publicado: (2014)

VEGF and sFLT-1 in serum of PIH patients and effects on the foetus
por: Tang, Yanhong, et al.
Publicado: (2019)

The sFlt-1/PlGF Ratio Trend Is Useful in Predicting Preeclampsia Severity in Hyperreactio Luteinalis Complicated with Preeclampsia
por: Miyatake, Risa, et al.
Publicado: (2023)

An Increase in Vascular Endothelial Growth Factor (VEGF) and VEGF Soluble Receptor-1 (sFlt-1) Are Associated with Early Recurrent Spontaneous Abortion
por: Pang, Lihong, et al.
Publicado: (2013)

Clinical value of serum VEGF and sFlt-1 in pernicious placenta previa
por: Wang, Na, et al.
Publicado: (2021)

Mechanical Forces Induce Changes in VEGF and VEGFR-1/sFlt-1 Expression in Human Chondrocytes
por: Beckmann, Rainer, et al.
Publicado: (2014)

Atypical preeclampsia before 20 weeks of gestation with multicystic placenta, hyperreactio luteinalis, and elevated sFlt-1/PlGF ratio as manifestations of fetal triploidy: A case report
por: Hayashida, Harue, et al.
Publicado: (2021)

Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia
por: Iriyama, Takayuki, et al.
Publicado: (2019)

A simple detection method for the serum sFLT1 protein in preeclampsia
por: Shibuya, Masabumi, et al.
Publicado: (2021)

sFLT1, PlGF, the sFLT1/PlGF Ratio and Their Association with Pre-Eclampsia in Twin Pregnancies—A Review of the Literature
por: Sapantzoglou, Ioakeim, et al.
Publicado: (2023)

Difference of concentration of placental soluble fms-like tyrosine kinase-1(sFlt-1), placental growth factor (PlGF), and sFlt-1/PlGF ratio in severe preeclampsia and normal pregnancy
por: Gurnadi, Jeffry Iman, et al.
Publicado: (2015)

Serum Soluble Fms-Like Tyrosine Kinase 1 (sFlt-1) Predicts the Severity of Acute Pancreatitis
por: Dumnicka, Paulina, et al.
Publicado: (2016)

RNAi Modulation of Placental sFLT1 for the Treatment of Preeclampsia.
por: Turanov, Anton A., et al.
Publicado: (2018)

sFlt-1 in Chronic Kidney Disease: Friend or Foe?
por: Matsui, Masaru, et al.
Publicado: (2022)

Production of an anti-angiogenic factor sFLT1 is suppressed via promoter hypermethylation of FLT1 gene in choriocarcinoma cells
por: Sasagawa, Tadashi, et al.
Publicado: (2020)

Short-term prediction of preeclampsia using the sFlt-1/PlGF ratio: a subanalysis of pregnant Japanese women from the PROGNOSIS Asia study
por: Ohkuchi, Akihide, et al.
Publicado: (2021)

Efficiency of sFlt-1/PlGF Ratio in Preeclampsia Diagnosis
por: Tataru-Copos, Anca-Florina, et al.
Publicado: (2022)

Predicting Preeclampsia Pregnancy Termination Time Using sFlt-1
por: Tanaka, Hiroaki, et al.
Publicado: (2022)

Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study
por: Alves, Brunna E, et al.
Publicado: (2011)

Release of soluble vascular endothelial growth factor receptor-1 (sFlt-1) during coronary artery bypass surgery
por: Denizot, Yves, et al.
Publicado: (2007)

Elevation of maternal serum sFlt-1 in pregnancy with mirror syndrome caused by fetal cardiac failure
por: Katoh, Yoshihisa, et al.
Publicado: (2018)

Reduced expression in preterm birth of sFLT-1 and PlGF with a high sFLT-1/PlGF ratio in extracellular vesicles suggests a potential biomarker
por: Hussein, Sama, et al.
Publicado: (2022)

Inducible Overexpression of sFlt-1 in Podocytes Ameliorates Glomerulopathy in Diabetic Mice
por: Ku, Ching-Hsin, et al.
Publicado: (2008)

Unfractionated heparin displaces sFlt-1 from the placental extracellular matrix
por: Moore, Kyle H., et al.
Publicado: (2020)

Trophoblast-Targeted Nanomedicine Modulates Placental sFLT1 for Preeclampsia Treatment
por: Li, Lei, et al.
Publicado: (2020)

MIF Increases sFLT1 Expression in Early Uncomplicated Pregnancy and Preeclampsia
por: Yong, Qing, et al.
Publicado: (2023)

The VEGF-A inhibitor sFLT-1 improves renal function by reducing endothelial activation and inflammation in a mouse model of type 1 diabetes
por: Bus, Pascal, et al.
Publicado: (2017)

Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase
por: Oe, Yuji, et al.
Publicado: (2018)

Attenuation of VEGFR-2 Expression by sFlt-1 and Low Oxygen in Human Placenta
por: Nevo, Ori, et al.
Publicado: (2013)

Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of Preeclampsia
por: Souders, Colby A., et al.
Publicado: (2015)

In Vivo Experiments Reveal the Good, the Bad and the Ugly Faces of sFlt-1 in Pregnancy
por: Szalai, Gabor, et al.
Publicado: (2014)

Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization
por: Wild, Raphael, et al.
Publicado: (2017)

Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1
por: Eslani, Medi, et al.
Publicado: (2017)

Enhanced Serum Levels of sFlt1: Impact on Materno–Fetal CMV Transmission
por: Penka, Lukas, et al.
Publicado: (2020)

Diagnostic accuracy of sFlt1/PlGF ratio as a marker for preeclampsia
por: Nikuei, Pooneh, et al.
Publicado: (2020)

Correlation between 25-Hydroxyvitamin D, sFlt-1, PLGF, and Hypertension in Pregnancy
por: Wang, Wei, et al.
Publicado: (2021)

Placental and maternal sFlt1/PlGF expression in gestational diabetes mellitus
por: Nuzzo, Anna Maria, et al.
Publicado: (2021)

Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1
por: Davis, Sarah M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kls3a7k5tk9b3rec6jrv4o83ph