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The formation of an aberrant PAX5 transcript in a patient with mixed phenotype acute leukemia harboring der(9)t(7;9)(q11.2;p13)

We experienced the case of a 56-year-old male with B-lymphoid/myeloid lineage mixed phenotype acute leukemia (MPAL). A cytogenetic analysis of the patient's bone marrow revealed a complex karyotype, including der(9)t(7;9)(q11.2;p13). We identified an aberrant PAX5 transcript, including the exon...

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Detalles Bibliográficos
Autores principales: Amaki, Jun, Matsushita, Hiromichi, Kitamura, Yuka, Nagao, Ryoko, Murayama, Hiromichi, Kojima, Minoru, Ando, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840422/
https://www.ncbi.nlm.nih.gov/pubmed/27144120
http://dx.doi.org/10.1016/j.lrr.2016.04.001

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