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Sulfasalazine: A rare cause of acute eosinophilic pneumonia
Sulfasalazine is a compound of 5-aminosalicylic acid (5-ASA) and sulfapyridine joined by an azo bond. It is a widely used drug in the treatment of chronic inflammatory bowel disease. Fatal toxicity of sulfasalazine arises from its effects on the bone marrow and the resulting blood dyscrasias. Pulmon...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840476/ https://www.ncbi.nlm.nih.gov/pubmed/27144116 http://dx.doi.org/10.1016/j.rmcr.2016.03.006 |
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author | Nadarajan, P. Fabre, A. Kelly, E. |
author_facet | Nadarajan, P. Fabre, A. Kelly, E. |
author_sort | Nadarajan, P. |
collection | PubMed |
description | Sulfasalazine is a compound of 5-aminosalicylic acid (5-ASA) and sulfapyridine joined by an azo bond. It is a widely used drug in the treatment of chronic inflammatory bowel disease. Fatal toxicity of sulfasalazine arises from its effects on the bone marrow and the resulting blood dyscrasias. Pulmonary toxicity from sulfasalazine is a rather rare finding. Here, we present the case of a patient who developed acute eosinophilic pneumonia with sulfasalazine use. |
format | Online Article Text |
id | pubmed-4840476 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-48404762016-05-03 Sulfasalazine: A rare cause of acute eosinophilic pneumonia Nadarajan, P. Fabre, A. Kelly, E. Respir Med Case Rep Case Report Sulfasalazine is a compound of 5-aminosalicylic acid (5-ASA) and sulfapyridine joined by an azo bond. It is a widely used drug in the treatment of chronic inflammatory bowel disease. Fatal toxicity of sulfasalazine arises from its effects on the bone marrow and the resulting blood dyscrasias. Pulmonary toxicity from sulfasalazine is a rather rare finding. Here, we present the case of a patient who developed acute eosinophilic pneumonia with sulfasalazine use. Elsevier 2016-03-22 /pmc/articles/PMC4840476/ /pubmed/27144116 http://dx.doi.org/10.1016/j.rmcr.2016.03.006 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Nadarajan, P. Fabre, A. Kelly, E. Sulfasalazine: A rare cause of acute eosinophilic pneumonia |
title | Sulfasalazine: A rare cause of acute eosinophilic pneumonia |
title_full | Sulfasalazine: A rare cause of acute eosinophilic pneumonia |
title_fullStr | Sulfasalazine: A rare cause of acute eosinophilic pneumonia |
title_full_unstemmed | Sulfasalazine: A rare cause of acute eosinophilic pneumonia |
title_short | Sulfasalazine: A rare cause of acute eosinophilic pneumonia |
title_sort | sulfasalazine: a rare cause of acute eosinophilic pneumonia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840476/ https://www.ncbi.nlm.nih.gov/pubmed/27144116 http://dx.doi.org/10.1016/j.rmcr.2016.03.006 |
work_keys_str_mv | AT nadarajanp sulfasalazineararecauseofacuteeosinophilicpneumonia AT fabrea sulfasalazineararecauseofacuteeosinophilicpneumonia AT kellye sulfasalazineararecauseofacuteeosinophilicpneumonia |