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Sulfasalazine: A rare cause of acute eosinophilic pneumonia

Sulfasalazine is a compound of 5-aminosalicylic acid (5-ASA) and sulfapyridine joined by an azo bond. It is a widely used drug in the treatment of chronic inflammatory bowel disease. Fatal toxicity of sulfasalazine arises from its effects on the bone marrow and the resulting blood dyscrasias. Pulmon...

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Autores principales: Nadarajan, P., Fabre, A., Kelly, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840476/
https://www.ncbi.nlm.nih.gov/pubmed/27144116
http://dx.doi.org/10.1016/j.rmcr.2016.03.006
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author Nadarajan, P.
Fabre, A.
Kelly, E.
author_facet Nadarajan, P.
Fabre, A.
Kelly, E.
author_sort Nadarajan, P.
collection PubMed
description Sulfasalazine is a compound of 5-aminosalicylic acid (5-ASA) and sulfapyridine joined by an azo bond. It is a widely used drug in the treatment of chronic inflammatory bowel disease. Fatal toxicity of sulfasalazine arises from its effects on the bone marrow and the resulting blood dyscrasias. Pulmonary toxicity from sulfasalazine is a rather rare finding. Here, we present the case of a patient who developed acute eosinophilic pneumonia with sulfasalazine use.
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spelling pubmed-48404762016-05-03 Sulfasalazine: A rare cause of acute eosinophilic pneumonia Nadarajan, P. Fabre, A. Kelly, E. Respir Med Case Rep Case Report Sulfasalazine is a compound of 5-aminosalicylic acid (5-ASA) and sulfapyridine joined by an azo bond. It is a widely used drug in the treatment of chronic inflammatory bowel disease. Fatal toxicity of sulfasalazine arises from its effects on the bone marrow and the resulting blood dyscrasias. Pulmonary toxicity from sulfasalazine is a rather rare finding. Here, we present the case of a patient who developed acute eosinophilic pneumonia with sulfasalazine use. Elsevier 2016-03-22 /pmc/articles/PMC4840476/ /pubmed/27144116 http://dx.doi.org/10.1016/j.rmcr.2016.03.006 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nadarajan, P.
Fabre, A.
Kelly, E.
Sulfasalazine: A rare cause of acute eosinophilic pneumonia
title Sulfasalazine: A rare cause of acute eosinophilic pneumonia
title_full Sulfasalazine: A rare cause of acute eosinophilic pneumonia
title_fullStr Sulfasalazine: A rare cause of acute eosinophilic pneumonia
title_full_unstemmed Sulfasalazine: A rare cause of acute eosinophilic pneumonia
title_short Sulfasalazine: A rare cause of acute eosinophilic pneumonia
title_sort sulfasalazine: a rare cause of acute eosinophilic pneumonia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840476/
https://www.ncbi.nlm.nih.gov/pubmed/27144116
http://dx.doi.org/10.1016/j.rmcr.2016.03.006
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AT fabrea sulfasalazineararecauseofacuteeosinophilicpneumonia
AT kellye sulfasalazineararecauseofacuteeosinophilicpneumonia