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Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization

There is growing evidence that defective DNA repair in neurons with accumulation of DNA lesions and loss of genome integrity underlies aging and many neurodegenerative disorders. An important challenge is to understand how neurons can tolerate the accumulation of persistent DNA lesions without trigg...

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Detalles Bibliográficos
Autores principales:	Mata-Garrido, Jorge, Casafont, Iñigo, Tapia, Olga, Berciano, Maria T., Lafarga, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840862/ https://www.ncbi.nlm.nih.gov/pubmed/27102221 http://dx.doi.org/10.1186/s40478-016-0312-9

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