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Empirical estimation of sequencing error rates using smoothing splines
BACKGROUND: Next-generation sequencing has been used by investigators to address a diverse range of biological problems through, for example, polymorphism and mutation discovery and microRNA profiling. However, compared to conventional sequencing, the error rates for next-generation sequencing are o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840868/ https://www.ncbi.nlm.nih.gov/pubmed/27102907 http://dx.doi.org/10.1186/s12859-016-1052-3 |