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N-glycosylation of R-spondin1 at Asn137 negatively regulates its secretion and Wnt/β-catenin signaling-enhancing activity

N-glycosylation is a post-translational protein modification with a wide variety of functions. It has been predicted that R-spondin1 (RSPO1) is N-glycosylated, although this remains unknown. The present study identified that RSPO1 was N-glycosylated at Asn137, and that N-glycosylation of RSPO1 negat...

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Detalles Bibliográficos
Autores principales:	TSUCHIYA, MIYU, NIWA, YUKI, SIMIZU, SIRO
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841080/ https://www.ncbi.nlm.nih.gov/pubmed/27123103 http://dx.doi.org/10.3892/ol.2016.4425

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