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BioTapestry now provides a web application and improved drawing and layout tools

Gene regulatory networks (GRNs) control embryonic development, and to understand this process in depth, researchers need to have a detailed understanding of both the network architecture and its dynamic evolution over time and space. Interactive visualization tools better enable researchers to conce...

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Detalles Bibliográficos
Autores principales: Paquette, Suzanne M., Leinonen, Kalle, Longabaugh, William J.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841208/
https://www.ncbi.nlm.nih.gov/pubmed/27134726
http://dx.doi.org/10.12688/f1000research.7620.1
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author Paquette, Suzanne M.
Leinonen, Kalle
Longabaugh, William J.R.
author_facet Paquette, Suzanne M.
Leinonen, Kalle
Longabaugh, William J.R.
author_sort Paquette, Suzanne M.
collection PubMed
description Gene regulatory networks (GRNs) control embryonic development, and to understand this process in depth, researchers need to have a detailed understanding of both the network architecture and its dynamic evolution over time and space. Interactive visualization tools better enable researchers to conceptualize, understand, and share GRN models. BioTapestry is an established application designed to fill this role, and recent enhancements released in Versions 6 and 7 have targeted two major facets of the program. First, we introduced significant improvements for network drawing and automatic layout that have now made it much easier for the user to create larger, more organized network drawings. Second, we revised the program architecture so it could continue to support the current Java desktop Editor program, while introducing a new BioTapestry GRN Viewer that runs as a JavaScript web application in a browser. We have deployed a number of GRN models using this new web application. These improvements will ensure that BioTapestry remains viable as a research tool in the face of the continuing evolution of web technologies, and as our understanding of GRN models grows.
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spelling pubmed-48412082016-04-29 BioTapestry now provides a web application and improved drawing and layout tools Paquette, Suzanne M. Leinonen, Kalle Longabaugh, William J.R. F1000Res Software Tool Article Gene regulatory networks (GRNs) control embryonic development, and to understand this process in depth, researchers need to have a detailed understanding of both the network architecture and its dynamic evolution over time and space. Interactive visualization tools better enable researchers to conceptualize, understand, and share GRN models. BioTapestry is an established application designed to fill this role, and recent enhancements released in Versions 6 and 7 have targeted two major facets of the program. First, we introduced significant improvements for network drawing and automatic layout that have now made it much easier for the user to create larger, more organized network drawings. Second, we revised the program architecture so it could continue to support the current Java desktop Editor program, while introducing a new BioTapestry GRN Viewer that runs as a JavaScript web application in a browser. We have deployed a number of GRN models using this new web application. These improvements will ensure that BioTapestry remains viable as a research tool in the face of the continuing evolution of web technologies, and as our understanding of GRN models grows. F1000Research 2016-01-08 /pmc/articles/PMC4841208/ /pubmed/27134726 http://dx.doi.org/10.12688/f1000research.7620.1 Text en Copyright: © 2016 Paquette SM et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The author(s) is/are employees of the US Government and therefore domestic copyright protection in USA does not apply to this work. The work may be protected under the copyright laws of other jurisdictions when used in those jurisdictions.
spellingShingle Software Tool Article
Paquette, Suzanne M.
Leinonen, Kalle
Longabaugh, William J.R.
BioTapestry now provides a web application and improved drawing and layout tools
title BioTapestry now provides a web application and improved drawing and layout tools
title_full BioTapestry now provides a web application and improved drawing and layout tools
title_fullStr BioTapestry now provides a web application and improved drawing and layout tools
title_full_unstemmed BioTapestry now provides a web application and improved drawing and layout tools
title_short BioTapestry now provides a web application and improved drawing and layout tools
title_sort biotapestry now provides a web application and improved drawing and layout tools
topic Software Tool Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841208/
https://www.ncbi.nlm.nih.gov/pubmed/27134726
http://dx.doi.org/10.12688/f1000research.7620.1
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