Biocompatibility of Portland Cement Modified with Titanium Oxide and Calcium Chloride in a Rat Model

INTRODUCTION: The aim of the present study was to evaluate the biocompatibility of two modified formulations of Portland cement (PC) mixed with either titanium oxide or both titanium oxide and calcium chloride. METHODS AND MATERIALS: Polyethylene tubes were filled with modified PCs or Angelus MTA as...

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Detalles Bibliográficos
Autores principales: Hoshyari, Narjes, Labbaf, Hossein, Jalayer Naderi, Nooshin, Kazemi, Ali, Bastami, Farshid, Koopaei, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Center for Endodontic Research 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841348/
https://www.ncbi.nlm.nih.gov/pubmed/27141221
http://dx.doi.org/10.7508/iej.2016.02.010
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author Hoshyari, Narjes
Labbaf, Hossein
Jalayer Naderi, Nooshin
Kazemi, Ali
Bastami, Farshid
Koopaei, Maryam
author_facet Hoshyari, Narjes
Labbaf, Hossein
Jalayer Naderi, Nooshin
Kazemi, Ali
Bastami, Farshid
Koopaei, Maryam
author_sort Hoshyari, Narjes
collection PubMed
description INTRODUCTION: The aim of the present study was to evaluate the biocompatibility of two modified formulations of Portland cement (PC) mixed with either titanium oxide or both titanium oxide and calcium chloride. METHODS AND MATERIALS: Polyethylene tubes were filled with modified PCs or Angelus MTA as the control; the tubes were then implanted in 28 Wistar rats subcutaneously. One tube was left empty as a negative control in each rat. Histologic samples were taken after 7, 15, 30 and 60 days. Sections were assessed histologically for inflammatory responses and presence of fibrous capsule and granulation tissue formation. Data were analyzed using the Fisher’s exact and Kruskal-Wallis tests. RESULT: PC mixed with titanium oxide showed the highest mean scores of inflammation compared with others. There was no statistically significant difference in the mean inflammatory grades between all groups in each of the understudy time intervals. CONCLUSION: The results showed favorable biocompatibility of these modified PC mixed with calcium chloride and titanium oxide.
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spelling pubmed-48413482016-05-02 Biocompatibility of Portland Cement Modified with Titanium Oxide and Calcium Chloride in a Rat Model Hoshyari, Narjes Labbaf, Hossein Jalayer Naderi, Nooshin Kazemi, Ali Bastami, Farshid Koopaei, Maryam Iran Endod J Original Article INTRODUCTION: The aim of the present study was to evaluate the biocompatibility of two modified formulations of Portland cement (PC) mixed with either titanium oxide or both titanium oxide and calcium chloride. METHODS AND MATERIALS: Polyethylene tubes were filled with modified PCs or Angelus MTA as the control; the tubes were then implanted in 28 Wistar rats subcutaneously. One tube was left empty as a negative control in each rat. Histologic samples were taken after 7, 15, 30 and 60 days. Sections were assessed histologically for inflammatory responses and presence of fibrous capsule and granulation tissue formation. Data were analyzed using the Fisher’s exact and Kruskal-Wallis tests. RESULT: PC mixed with titanium oxide showed the highest mean scores of inflammation compared with others. There was no statistically significant difference in the mean inflammatory grades between all groups in each of the understudy time intervals. CONCLUSION: The results showed favorable biocompatibility of these modified PC mixed with calcium chloride and titanium oxide. Iranian Center for Endodontic Research 2016 2016-03-20 /pmc/articles/PMC4841348/ /pubmed/27141221 http://dx.doi.org/10.7508/iej.2016.02.010 Text en © 2016, Iranian Center for Endodontic Research This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Hoshyari, Narjes
Labbaf, Hossein
Jalayer Naderi, Nooshin
Kazemi, Ali
Bastami, Farshid
Koopaei, Maryam
Biocompatibility of Portland Cement Modified with Titanium Oxide and Calcium Chloride in a Rat Model
title Biocompatibility of Portland Cement Modified with Titanium Oxide and Calcium Chloride in a Rat Model
title_full Biocompatibility of Portland Cement Modified with Titanium Oxide and Calcium Chloride in a Rat Model
title_fullStr Biocompatibility of Portland Cement Modified with Titanium Oxide and Calcium Chloride in a Rat Model
title_full_unstemmed Biocompatibility of Portland Cement Modified with Titanium Oxide and Calcium Chloride in a Rat Model
title_short Biocompatibility of Portland Cement Modified with Titanium Oxide and Calcium Chloride in a Rat Model
title_sort biocompatibility of portland cement modified with titanium oxide and calcium chloride in a rat model
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841348/
https://www.ncbi.nlm.nih.gov/pubmed/27141221
http://dx.doi.org/10.7508/iej.2016.02.010
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