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CADM1/TSLC1 Identifies HTLV-1-Infected Cells and Determines Their Susceptibility to CTL-Mediated Lysis

Human T cell lymphotropic virus-1 (HTLV-1) primarily infects CD4(+) T cells, causing inflammatory disorders or a T cell malignancy in 5% to 10% of carriers. The cytotoxic T lymphocyte (CTL) response is a key factor that controls the viral load and thus the risk of disease. The ability to detect the...

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Detalles Bibliográficos
Autores principales: Manivannan, Kiruthika, Rowan, Aileen G., Tanaka, Yuetsu, Taylor, Graham P., Bangham, Charles R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841533/
https://www.ncbi.nlm.nih.gov/pubmed/27105228
http://dx.doi.org/10.1371/journal.ppat.1005560

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