Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA

Neisseria adhesin A (NadA) is present on the meningococcal surface and contributes to adhesion to and invasion of human cells. NadA is also one of three recombinant antigens in the recently-approved Bexsero vaccine, which protects against serogroup B meningococcus. The amount of NadA on the bacteria...

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Detalles Bibliográficos
Autores principales: Liguori, Alessia, Malito, Enrico, Lo Surdo, Paola, Fagnocchi, Luca, Cantini, Francesca, Haag, Andreas F., Brier, Sébastien, Pizza, Mariagrazia, Delany, Isabel, Bottomley, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841544/
https://www.ncbi.nlm.nih.gov/pubmed/27105075
http://dx.doi.org/10.1371/journal.ppat.1005557

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