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Optimization of the All-D Peptide D3 for Aβ Oligomer Elimination

The aggregation of amyloid-β (Aβ) is postulated to be the crucial event in Alzheimer’s disease (AD). In particular, small neurotoxic Aβ oligomers are considered to be responsible for the development and progression of AD. Therefore, elimination of thesis oligomers represents a potential causal thera...

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Detalles Bibliográficos
Autores principales: Klein, Antonia Nicole, Ziehm, Tamar, Tusche, Markus, Buitenhuis, Johan, Bartnik, Dirk, Boeddrich, Annett, Wiglenda, Thomas, Wanker, Erich, Funke, Susanne Aileen, Brener, Oleksandr, Gremer, Lothar, Kutzsche, Janine, Willbold, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841555/
https://www.ncbi.nlm.nih.gov/pubmed/27105346
http://dx.doi.org/10.1371/journal.pone.0153035