Cargando…
Alterations of Dermal Connective Tissue Collagen in Diabetes: Molecular Basis of Aged-Appearing Skin
Alterations of the collagen, the major structural protein in skin, contribute significantly to human skin connective tissue aging. As aged-appearing skin is more common in diabetes, here we investigated the molecular basis of aged-appearing skin in diabetes. Among all known human matrix metalloprote...
Autores principales: | Argyropoulos, Angela J., Robichaud, Patrick, Balimunkwe, Rebecca Mutesi, Fisher, Gary J., Hammerberg, Craig, Yan, Yan, Quan, Taihao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841569/ https://www.ncbi.nlm.nih.gov/pubmed/27104752 http://dx.doi.org/10.1371/journal.pone.0153806 |
Ejemplares similares
-
Elevated Matrix Metalloproteinases and Collagen Fragmentation in Photodamaged Human Skin: Impact of Altered Extracellular Matrix Microenvironment on Dermal Fibroblast Function
por: Quan, Taihao, et al.
Publicado: (2013) -
Oxidant Exposure Induces Cysteine-Rich Protein 61 (CCN1) via c-Jun/AP-1 to Reduce Collagen Expression in Human Dermal Fibroblasts
por: Qin, Zhaoping, et al.
Publicado: (2014) -
Age-associated reduction of cellular spreading/mechanical force up-regulates matrix metalloproteinase-1 expression and collagen fibril fragmentation via c-Jun/AP-1 in human dermal fibroblasts
por: Qin, Zhaoping, et al.
Publicado: (2014) -
Actin cytoskeleton assembly regulates collagen production via TGF‐β type II receptor in human skin fibroblasts
por: Qin, Zhaoping, et al.
Publicado: (2018) -
YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts
por: Qin, Zhaoping, et al.
Publicado: (2018)