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Factors Interfering with Delineation on MRCP of Pancreaticobiliary Maljunction in Paediatric Patients

BACKGROUND: The aim of this study was to assess factors for delineating the pancreaticobiliary junction in the presence of pediatric congenital choledochal cysts (CCC) using Magnetic resonance cholangiopancreatography (MRCP). METHODS: Retrospective review of medical records for 48 patients with CCC...

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Autores principales: Huang, Shun-gen, Guo, Wan-liang, Wang, Jian, Sheng, Mao, Lan, Xing-hao, Fang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841599/
https://www.ncbi.nlm.nih.gov/pubmed/27104956
http://dx.doi.org/10.1371/journal.pone.0154178
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author Huang, Shun-gen
Guo, Wan-liang
Wang, Jian
Sheng, Mao
Lan, Xing-hao
Fang, Lin
author_facet Huang, Shun-gen
Guo, Wan-liang
Wang, Jian
Sheng, Mao
Lan, Xing-hao
Fang, Lin
author_sort Huang, Shun-gen
collection PubMed
description BACKGROUND: The aim of this study was to assess factors for delineating the pancreaticobiliary junction in the presence of pediatric congenital choledochal cysts (CCC) using Magnetic resonance cholangiopancreatography (MRCP). METHODS: Retrospective review of medical records for 48 patients with CCC was conducted, including demographics, biliary amylase and MRCP findings if available. With univariate and multivariate logistic regression, we measured significant factors affecting pancreaticobiliary maljunction(PBM) diagnoses by MRCP. RESULTS: Of the subjects enrolled with CCC. Twenty-eight cases had PBM according to MRCP. Univariate analysis confirmed that age, cyst diameter > 30 mm and cysts that descended to the introitus pelvis affected junctional delineation and detection of PBM (P<0.05). Stepwise logistic regression analysis confirmed large cysts in the introitus pelvis predicted pancreaticobiliary junctional delineation in MRCP and these data agreed with the literature. A correlation between cyst diameter and the length of the common channel was found as was cyst diameter and biliary amylase although there were no significant differences between them. CONCLUSIONS: Age, cyst diameter >30 mm and descending cysts into the introitus pelvis affected junctional delineation of the pancreatic and bile duct in PBM with MRCP. Large cyst descension into the introitus pelvis was an independent factors affecting PBM detection.
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spelling pubmed-48415992016-04-29 Factors Interfering with Delineation on MRCP of Pancreaticobiliary Maljunction in Paediatric Patients Huang, Shun-gen Guo, Wan-liang Wang, Jian Sheng, Mao Lan, Xing-hao Fang, Lin PLoS One Research Article BACKGROUND: The aim of this study was to assess factors for delineating the pancreaticobiliary junction in the presence of pediatric congenital choledochal cysts (CCC) using Magnetic resonance cholangiopancreatography (MRCP). METHODS: Retrospective review of medical records for 48 patients with CCC was conducted, including demographics, biliary amylase and MRCP findings if available. With univariate and multivariate logistic regression, we measured significant factors affecting pancreaticobiliary maljunction(PBM) diagnoses by MRCP. RESULTS: Of the subjects enrolled with CCC. Twenty-eight cases had PBM according to MRCP. Univariate analysis confirmed that age, cyst diameter > 30 mm and cysts that descended to the introitus pelvis affected junctional delineation and detection of PBM (P<0.05). Stepwise logistic regression analysis confirmed large cysts in the introitus pelvis predicted pancreaticobiliary junctional delineation in MRCP and these data agreed with the literature. A correlation between cyst diameter and the length of the common channel was found as was cyst diameter and biliary amylase although there were no significant differences between them. CONCLUSIONS: Age, cyst diameter >30 mm and descending cysts into the introitus pelvis affected junctional delineation of the pancreatic and bile duct in PBM with MRCP. Large cyst descension into the introitus pelvis was an independent factors affecting PBM detection. Public Library of Science 2016-04-22 /pmc/articles/PMC4841599/ /pubmed/27104956 http://dx.doi.org/10.1371/journal.pone.0154178 Text en © 2016 Huang et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Huang, Shun-gen
Guo, Wan-liang
Wang, Jian
Sheng, Mao
Lan, Xing-hao
Fang, Lin
Factors Interfering with Delineation on MRCP of Pancreaticobiliary Maljunction in Paediatric Patients
title Factors Interfering with Delineation on MRCP of Pancreaticobiliary Maljunction in Paediatric Patients
title_full Factors Interfering with Delineation on MRCP of Pancreaticobiliary Maljunction in Paediatric Patients
title_fullStr Factors Interfering with Delineation on MRCP of Pancreaticobiliary Maljunction in Paediatric Patients
title_full_unstemmed Factors Interfering with Delineation on MRCP of Pancreaticobiliary Maljunction in Paediatric Patients
title_short Factors Interfering with Delineation on MRCP of Pancreaticobiliary Maljunction in Paediatric Patients
title_sort factors interfering with delineation on mrcp of pancreaticobiliary maljunction in paediatric patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841599/
https://www.ncbi.nlm.nih.gov/pubmed/27104956
http://dx.doi.org/10.1371/journal.pone.0154178
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