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Tumor suppressor properties of the splicing regulatory factor RBM10

RBM10 is an RNA binding protein and alternative splicing regulator frequently mutated in lung adenocarcinomas. Recent results indicate that RBM10 inhibits proliferation of lung cancer cells by promoting skipping of exon 9 of the gene NUMB, a frequent alternative splicing change in lung cancer genera...

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Detalles Bibliográficos
Autores principales:	Hernández, Jordi, Bechara, Elias, Schlesinger, Doerte, Delgado, Javier, Serrano, Luis, Valcárcel, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841610/ https://www.ncbi.nlm.nih.gov/pubmed/26853560 http://dx.doi.org/10.1080/15476286.2016.1144004

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