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Can We Repurpose FDA-Approved Alefacept to Diminish the HIV Reservoir?

Current anti-retroviral treatment (ART) for HIV is effective in maintaining HIV at undetectable levels. However, cessation of ART results in immediate and brisk rebound of viremia to high levels. This rebound is driven by an HIV reservoir mainly enriched in memory CD4(+) T cells. In order to provide...

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Detalles Bibliográficos
Autores principales: Zaidi, Asifa, Meng, Qinglai, Popkin, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841618/
https://www.ncbi.nlm.nih.gov/pubmed/27110598
http://dx.doi.org/10.4172/imt.1000104