Absolute quantification reveals the stable transmission of a high copy number variant linked to autoinflammatory disease

BACKGROUND: Dissecting the role copy number variants (CNVs) play in disease pathogenesis is directly reliant on accurate methods for quantification. The Shar-Pei dog breed is predisposed to a complex autoinflammatory disease with numerous clinical manifestations. One such sign, recurrent fever, was...

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Detalles Bibliográficos
Autores principales: Olsson, M., Kierczak, M., Karlsson, Å., Jabłońska, J., Leegwater, P., Koltookian, M., Abadie, J., De Citres, C. Dufaure, Thomas, A., Hedhammar, Å., Tintle, L., Lindblad-Toh, K., Meadows, J. R. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841964/
https://www.ncbi.nlm.nih.gov/pubmed/27107962
http://dx.doi.org/10.1186/s12864-016-2619-0

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