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LC-MS Method for Studying the Pharmacokinetics and Bioequivalence of Clonidine Hydrochloride in Healthy Male Volunteers

BACKGROUND: A simple and sensitive high performance liquid chromatography-electrospray ionization mass spectrometry method has been evaluated for the assignment of clonidine hydrochloride in human plasma. METHODS: The mobile phase composed of acetonitrile-water 60:40 (v/v) and 0.2% formic acid 20 μl...

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Detalles Bibliográficos
Autores principales: Danafar, Hossein, Hamidi, Mehrdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842247/
https://www.ncbi.nlm.nih.gov/pubmed/27141268