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LC-MS Method for Studying the Pharmacokinetics and Bioequivalence of Clonidine Hydrochloride in Healthy Male Volunteers
BACKGROUND: A simple and sensitive high performance liquid chromatography-electrospray ionization mass spectrometry method has been evaluated for the assignment of clonidine hydrochloride in human plasma. METHODS: The mobile phase composed of acetonitrile-water 60:40 (v/v) and 0.2% formic acid 20 μl...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Avicenna Research Institute
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842247/ https://www.ncbi.nlm.nih.gov/pubmed/27141268 |