HIV-1 capsid is involved in post-nuclear entry steps

BACKGROUND: HIV-1 capsid influences viral uncoating and nuclear import. Some capsid is detected in the nucleus but it is unclear if it has any function. We reported that the antibiotic Coumermycin-A1 (C-A1) inhibits HIV-1 integration and that a capsid mutation confers resistance to C-A1, suggesting...

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Detalles Bibliográficos
Autores principales: Chen, Nan-Yu, Zhou, Lihong, Gane, Paul J., Opp, Silvana, Ball, Neil J., Nicastro, Giuseppe, Zufferey, Madeleine, Buffone, Cindy, Luban, Jeremy, Selwood, David, Diaz-Griffero, Felipe, Taylor, Ian, Fassati, Ariberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842275/
https://www.ncbi.nlm.nih.gov/pubmed/27107820
http://dx.doi.org/10.1186/s12977-016-0262-0

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