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Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve

The presence of myocardial ischemia is the most important prognostic factor in patients with ischemic heart disease. Fractional flow reserve (FFR) is a gold standard invasive method used to detect the stenosis-specific myocardial ischemia. FFR-guided revascularization strategy is superior to angiogr...

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Autores principales: Hwang, Doyeon, Lee, Joo Myung, Koo, Bon-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842851/
https://www.ncbi.nlm.nih.gov/pubmed/27134520
http://dx.doi.org/10.3348/kjr.2016.17.3.307
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author Hwang, Doyeon
Lee, Joo Myung
Koo, Bon-Kwon
author_facet Hwang, Doyeon
Lee, Joo Myung
Koo, Bon-Kwon
author_sort Hwang, Doyeon
collection PubMed
description The presence of myocardial ischemia is the most important prognostic factor in patients with ischemic heart disease. Fractional flow reserve (FFR) is a gold standard invasive method used to detect the stenosis-specific myocardial ischemia. FFR-guided revascularization strategy is superior to angiography-guided strategy. The recently developed hyperemia-free index, instantaneous wave free ratio is being actively investigated. A non-invasive FFR derived from coronary CT angiography is now used in clinical practice. Due to rapid expansion of invasive and non-invasive physiologic assessment, comprehensive understanding of the role and potential pitfalls of each modality are required for its application. In this review, we focus on the basic and clinical aspects of physiologic assessment in ischemic heart disease.
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spelling pubmed-48428512016-05-01 Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve Hwang, Doyeon Lee, Joo Myung Koo, Bon-Kwon Korean J Radiol Cardiovascular Imaging The presence of myocardial ischemia is the most important prognostic factor in patients with ischemic heart disease. Fractional flow reserve (FFR) is a gold standard invasive method used to detect the stenosis-specific myocardial ischemia. FFR-guided revascularization strategy is superior to angiography-guided strategy. The recently developed hyperemia-free index, instantaneous wave free ratio is being actively investigated. A non-invasive FFR derived from coronary CT angiography is now used in clinical practice. Due to rapid expansion of invasive and non-invasive physiologic assessment, comprehensive understanding of the role and potential pitfalls of each modality are required for its application. In this review, we focus on the basic and clinical aspects of physiologic assessment in ischemic heart disease. The Korean Society of Radiology 2016 2016-04-14 /pmc/articles/PMC4842851/ /pubmed/27134520 http://dx.doi.org/10.3348/kjr.2016.17.3.307 Text en Copyright © 2016 The Korean Society of Radiology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cardiovascular Imaging
Hwang, Doyeon
Lee, Joo Myung
Koo, Bon-Kwon
Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve
title Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve
title_full Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve
title_fullStr Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve
title_full_unstemmed Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve
title_short Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve
title_sort physiologic assessment of coronary artery disease: focus on fractional flow reserve
topic Cardiovascular Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842851/
https://www.ncbi.nlm.nih.gov/pubmed/27134520
http://dx.doi.org/10.3348/kjr.2016.17.3.307
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