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Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve
The presence of myocardial ischemia is the most important prognostic factor in patients with ischemic heart disease. Fractional flow reserve (FFR) is a gold standard invasive method used to detect the stenosis-specific myocardial ischemia. FFR-guided revascularization strategy is superior to angiogr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Radiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842851/ https://www.ncbi.nlm.nih.gov/pubmed/27134520 http://dx.doi.org/10.3348/kjr.2016.17.3.307 |
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author | Hwang, Doyeon Lee, Joo Myung Koo, Bon-Kwon |
author_facet | Hwang, Doyeon Lee, Joo Myung Koo, Bon-Kwon |
author_sort | Hwang, Doyeon |
collection | PubMed |
description | The presence of myocardial ischemia is the most important prognostic factor in patients with ischemic heart disease. Fractional flow reserve (FFR) is a gold standard invasive method used to detect the stenosis-specific myocardial ischemia. FFR-guided revascularization strategy is superior to angiography-guided strategy. The recently developed hyperemia-free index, instantaneous wave free ratio is being actively investigated. A non-invasive FFR derived from coronary CT angiography is now used in clinical practice. Due to rapid expansion of invasive and non-invasive physiologic assessment, comprehensive understanding of the role and potential pitfalls of each modality are required for its application. In this review, we focus on the basic and clinical aspects of physiologic assessment in ischemic heart disease. |
format | Online Article Text |
id | pubmed-4842851 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Society of Radiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-48428512016-05-01 Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve Hwang, Doyeon Lee, Joo Myung Koo, Bon-Kwon Korean J Radiol Cardiovascular Imaging The presence of myocardial ischemia is the most important prognostic factor in patients with ischemic heart disease. Fractional flow reserve (FFR) is a gold standard invasive method used to detect the stenosis-specific myocardial ischemia. FFR-guided revascularization strategy is superior to angiography-guided strategy. The recently developed hyperemia-free index, instantaneous wave free ratio is being actively investigated. A non-invasive FFR derived from coronary CT angiography is now used in clinical practice. Due to rapid expansion of invasive and non-invasive physiologic assessment, comprehensive understanding of the role and potential pitfalls of each modality are required for its application. In this review, we focus on the basic and clinical aspects of physiologic assessment in ischemic heart disease. The Korean Society of Radiology 2016 2016-04-14 /pmc/articles/PMC4842851/ /pubmed/27134520 http://dx.doi.org/10.3348/kjr.2016.17.3.307 Text en Copyright © 2016 The Korean Society of Radiology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Cardiovascular Imaging Hwang, Doyeon Lee, Joo Myung Koo, Bon-Kwon Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve |
title | Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve |
title_full | Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve |
title_fullStr | Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve |
title_full_unstemmed | Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve |
title_short | Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve |
title_sort | physiologic assessment of coronary artery disease: focus on fractional flow reserve |
topic | Cardiovascular Imaging |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842851/ https://www.ncbi.nlm.nih.gov/pubmed/27134520 http://dx.doi.org/10.3348/kjr.2016.17.3.307 |
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