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NOTCH1 inhibition enhances the efficacy of conventional chemotherapeutic agents by targeting head neck cancer stem cell

Cancer stem cells (CSCs) are considered responsible for tumor initiation and chemoresistance. This study was aimed to investigate the possibility of targeting head neck squamous cell carcinoma (HNSCC) by NOTCH1 pathway inhibition and explore the synergistic effect of combining NOTCH inhibition with...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhi-Li, Zhang, Lu, Huang, Cong-Fa, Ma, Si-Rui, Bu, Lin-Lin, Liu, Jian-Feng, Yu, Guang-Tao, Liu, Bing, Gutkind, J. Silvio, Kulkarni, Ashok B., Zhang, Wen-Feng, Sun, Zhi-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842967/ https://www.ncbi.nlm.nih.gov/pubmed/27108536 http://dx.doi.org/10.1038/srep24704

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