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Identification of residues crucial for the interaction between human neuroglobin and the α-subunit of heterotrimeric G(i) protein
Mammalian neuroglobin (Ngb) protects neuronal cells under conditions of oxidative stress. We previously showed that human Ngb acts as a guanine nucleotide dissociation inhibitor (GDI) for the α-subunits of heterotrimeric G(i/o) proteins and inhibits the decrease in cAMP concentration, leading to pro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842972/ https://www.ncbi.nlm.nih.gov/pubmed/27109834 http://dx.doi.org/10.1038/srep24948 |