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Hedgehog signaling activation induces stem cell proliferation and hormone release in the adult pituitary gland

Hedgehog (HH) signaling is known to be essential during the embryonal development of the pituitary gland but the knowledge about its role in the adult pituitary and in associated tumors is sparse. In this report we investigated the effect of excess Hh signaling activation in murine pituitary explant...

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Detalles Bibliográficos
Autores principales: Pyczek, Joanna, Buslei, Rolf, Schult, David, Hölsken, Annett, Buchfelder, Michael, Heß, Ina, Hahn, Heidi, Uhmann, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842994/
https://www.ncbi.nlm.nih.gov/pubmed/27109116
http://dx.doi.org/10.1038/srep24928

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