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Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin
Accurate chromosome segregation during cell division is crucial for propagating life and protects from cellular transformation. The SKAP:Astrin heterodimer localizes to spindle microtubules and to mature microtubule–kinetochore attachments during mitosis. Depletion of either subunit disrupts spindle...
Autores principales: | Friese, Alexandra, Faesen, Alex C., Huis in ‘t Veld, Pim J., Fischböck, Josef, Prumbaum, Daniel, Petrovic, Arsen, Raunser, Stefan, Herzog, Franz, Musacchio, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843017/ https://www.ncbi.nlm.nih.gov/pubmed/27095104 http://dx.doi.org/10.1038/ncomms11407 |
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