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Tlr2 deficiency does not limit the development of left ventricular hypertrophy in a model of transverse aortic constriction induced pressure overload

BACKGROUND: Toll-like receptors (TLRs) are involved in a variety of cardiovascular disorders, including septic cardiomyopathy, ischemia/reperfusion, heart failure, and cardiac hypertrophy. Previous research revealed that TLR4 promotes cardiac hypertrophy in vivo. Therefore, we investigated whether T...

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Detalles Bibliográficos
Autores principales: Bualeong, Tippaporn, Kebir, Sied, Hof, Dorothea, Goelz, Lina, Graewe, Mathias, Ehrentraut, Stefan Felix, Knuefermann, Pascal, Baumgarten, Georg, Meyer, Rainer, Ehrentraut, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843197/
https://www.ncbi.nlm.nih.gov/pubmed/27109115
http://dx.doi.org/10.1186/s12952-016-0050-3

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