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Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract
BACKGROUND: Congenital heart disease is the most common type of birth defect, affecting ≈2% of the population. Malformations involving the cardiac outflow tract and semilunar valves account for >50% of these cases predominantly because of a bicuspid aortic valve, which has an estimated prevalence...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843530/ https://www.ncbi.nlm.nih.gov/pubmed/27107132 http://dx.doi.org/10.1161/JAHA.115.003075 |